Role of PATJ in Stroke Prognosis by modulating Endothelial to Mesenchymal Transition through the Hippo/Notch/PI3K Axis.

Abstract excerpt

<title>Abstract</title><p>Through GWAS studies we identified<italic>PATJ</italic>associated with functional outcome after ischemic stroke (IS). The aim of this study was to determine PATJ role in brain endothelial cells (ECs) in the context of stroke outcome.<italic>PATJ</italic>expression analyses in patient’s blood revealed that: (i) the risk allele of rs76221407 induces higher expression of<italic>PATJ</italic>...

Topics

Open a Topic to create a Post that cites this publication.

• Adipose Tissue and Metabolism
• Cancer, Hypoxia, and Metabolism
• High Altitude and Hypoxia

Identifiers and source

Literature Corpus work

83f09524-156a-5d17-81d8-5451314a2584

DOI

10.21203/rs.3.rs-3227150/v1