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Article

CircHAT1 regulates the proliferation and phenotype switch of vascular smooth muscle cells in lower extremity arteriosclerosis obliterans through targeting SFRS1.

Molecular and cellular biochemistry - 1 Jan 2025

Huang Xian-Ying, Fu Fang-Yong, Qian Kai, Feng Qiao-Li, Cao Sai, Wu Wei-Yu, Luo Yuan-Lin, Chen Wei-Jie, Zhang Zhi, Huang Shui-Chuan

Abstract excerpt

This study aimed to decipher the mechanism of circular ribonucleic acids (circRNAs) in lower extremity arteriosclerosis obliterans (LEASO). First, bioinformatics analysis was performed for screening significantly down-regulated cardiac specific circRNA-circHAT1 in LEASO. The expression of circHAT1 in LEASO clinical samples was detected by quantitative real-time polymerase chain reaction (qRT-PCR). The protein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38409514
DOI: 10.1007/s11010-024-04932-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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