A molecular brain atlas reveals cellular shifts during the repair phase of stroke

Abstract excerpt

Ischemic stroke triggers a cascade of pathological events that affect multiple cell types and often lead to incomplete functional recovery. Despite advances in single-cell technologies, the molecular and cellular responses that contribute to long-term post-stroke impairment remain poorly understood. To gain better insight into the underlying mechanisms, we generated a single-cell transcriptomic atlas from distinct...

Topics

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• Acute Ischemic Stroke Management
• Cancer-related molecular mechanisms research
• Genome-Wide Association Study
• Mutation
• Neuroinflammation and Neurodegeneration Mechanisms
• Retinal Diseases and Treatments
• Stroke
• Translational Research, Biomedical

Identifiers and source

Literature Corpus work

cf26f9c7-f6f5-58cc-b304-bbb4f698aadd

DOI

10.1101/2024.08.21.608971