Article

Dietary intervention targets hierarchical metabolic dependencies in human acute myeloid leukemia

2026-07-14

Abstract excerpt

<title>Abstract</title> <p> Acute myeloid leukemia (AML) is sustained by metabolic plasticity, enabling leukemic cells to adapt across cellular states and withstand therapeutic stress. Whether systemic manipulation of nutrient availability can expose metabolic dependencies in human leukemia remains unknown. We conducted a randomized metabolic intervention in patients with newly diagnosed AML undergoing induction...

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Literature Corpus work: 8c10f62e-eebc-57e6-bdd2-6bc992bc842a
DOI: 10.21203/rs.3.rs-9930778/v1

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