Article
The differential activation of metabolic pathways in leukemic cells depending on their genotype and micro-environmental stress.
Metabolomics : Official journal of the Metabolomic Society - 10 Jan 2020
Lo Presti Caroline, Fauvelle Florence, Mondet Julie, Mossuz Pascal
Abstract excerpt
INTRODUCTION: Acute myeloid leukemia (AML) is characterized by a set of malignant proliferations leading to an accumulation of blasts in the bone marrow and blood. The prognosis is pejorative due to the molecular complexity and pathways implicated in leukemogenesis. OBJECTIVES: Our research was focused on comparing the metabolic profiles of leukemic cells in basal culture and deprivation conditions to investigate...
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