Article

Cellular Allostatic Load is linked to Increased Energy Expenditure and Accelerated Biological Aging

2022-02-23

Abstract excerpt

Stress triggers anticipatory physiological responses that promote survival, a phenomenon termed allostasis. However, the chronic activation of energy-dependent allostatic responses results in allostatic load, a dysregulated state that predicts functional decline, accelerates aging, and increases mortality in humans. The energetic cost and cellular basis for the damaging effects of allostatic load have not been def...

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Literature Corpus work: bcb4f008-f2f9-5c76-ae2b-be6ec98ebf25
DOI: 10.1101/2022.02.22.481548

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