Article
Novel nuclear role of HDAC6 in prognosis and therapeutic target for colorectal cancer
2020-11-02
Abstract excerpt
Histone deacetylase 6 (HDAC6) inhibition is a potential treatment of a wide range of cancer types via the acetylation of diverse proteins in the cytoplasm. However, the regulation of histone acetylation and the maintenance of higher-order chromatin structure remains unidentified. Here, we investigated the effect of selective inhibition of HDAC6 by histone acetylation, chromatin relaxation assays, co-immunoprecipi...
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Identifiers and source
- Literature Corpus work
- 8bd2596f-614e-50dc-b0ff-9dbe25d32473
- DOI
- 10.1101/2020.11.02.356121