Histone deacetylase 6 in cancer

Abstract excerpt

Histone acetylation and deacetylation are important epigenetic mechanisms that regulate gene expression and transcription. Histone deacetylase 6 (HDAC6) is a unique member of the HDAC family that not only participates in histone acetylation and deacetylation but also targets several nonhistone substrates, such as α-tubulin, cortactin, and heat shock protein 90 (HSP90), to regulate cell proliferation, metastasis,...

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• Histone Deacetylase Inhibitors Research
• Peptidase Inhibition and Analysis
• Protein Degradation and Inhibitors