Article
The role of histone modifications and transposable elements in the epigenetic regulation of gene dosage after gene duplication
2024-11-20
Abstract excerpt
The duplication of genes has long been recognized as a substrate for evolutionary novelty and adaptation, but the factors that govern fixation of paralogs soon after duplication are only partially understood. Duplication often leads to an increase in gene dosage, or the amount of functional gene product. For genes with which an increased dosage is harmful (i.e., triplosensitive genes), a dosage balancing mechanism...
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Identifiers and source
- Literature Corpus work
- 8ba1e1a3-e9b6-5c0c-9774-aae475d677ca
- DOI
- 10.1101/2024.11.18.624187