Back to search

Article

Coregulation of tandem duplicate genes slows evolution of subfunctionalization in mammals

2015-05-10

Abstract excerpt

Gene duplication is a fundamental process in genome evolution. However, most young duplicates are degraded into pseudogenes by loss-of-function mutations, and the factors that allow some duplicate pairs to survive long-term remain controversial. One class of models to explain duplicate retention invokes sub- or neofunctionalization, especially through evolution of gene expression, while other models focus on shari...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e031eefe-64ac-503f-9cba-763523acb503
DOI
10.1101/019166
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Coregulation of tandem duplicate genes slows evolution of subfunctionalization in mammalsDOI 10.1101/019166
Select a neighboring publication to make it the new centre.