Article
Epigenetic changes and repositioning determine the evolutionary fate of duplicated genes.
Biochemistry. Biokhimiia - 1 May 2005
Rodin S N, Parkhomchuk D V, Riggs A D
Abstract excerpt
Consideration of epigenetic silencing, perhaps by DNA methylation, led to an epigenetic complementation (EC) model for evolution by gene duplication (Rodin and Riggs (2003) J. Mol. Evol., 56, 718-729). This and subsequent work on genome-wide analyses of gene duplicates in several eukaryotic species pointed to a fundamental link between localization in the genome, epigenetic regulation of expression, and the...
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