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Article

DNA methylation and evolution of duplicate genes.

Proceedings of the National Academy of Sciences of the United States of America - 22 Apr 2014

Keller Thomas E, Yi Soojin V

Abstract excerpt

The evolutionary mechanisms underlying duplicate gene maintenance and divergence remain highly debated. Epigenetic modifications, such as DNA methylation, may contribute to duplicate gene evolution by facilitating tissue-specific regulation. However, the role of epigenetic divergence on duplicate gene evolution remains little understood. Here we show, using comprehensive data across 10 diverse human tissues, that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

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Source

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Identifiers

PMID: 24711408
DOI: 10.1073/pnas.1321420111
PMCID: PMC4000835

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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