Article

Chromatin Structural Characteristics as an Evidence of Nonhomologous End Joining Repair Pathway Promoting TMPRSS2-ERG Gene Fusion in Prostatic Cancer

2023-06-02

Abstract excerpt

<h4>Background: </h4> TMPRSS2-ERG fusion is the most prevalent gene rearrangement found in prostate cancer and has been linked to prostate carcinogenesis. To investigate the formation mechanism of TMPRSS2-ERG fusion, we performed gene sequencing on ERG fusion prostate cancer and compared them with the normal gene sequence of the Hg19 human genome in the UCSC database. Methods We utilized online tools such as QGRS...

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Literature Corpus work: 8b70ed15-afcb-5354-af18-3078e8dca0bf
DOI: 10.21203/rs.3.rs-2879043/v1

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