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Multi-ancestry Multivariate Genome-Wide Analysis Highlights the Role of Common Genetic Variation in Cardiac Structure, Function, and Heart Failure-related Traits

2021-08-05

Abstract excerpt

<h4>ABSTRACT</h4> Heart failure (HF) is a leading cause of cardiovascular morbidity and mortality, yet the contribution of common genetic variation to HF risk has not been fully elucidated, particularly in comparison to other common cardiometabolic traits. We conducted a multi-ancestry genome-wide association study (GWAS) meta-analysis of all-cause HF including up to 56,722 HF cases and 1,133,054 controls, identif...

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Literature Corpus work
8b686a08-78eb-507f-bbee-d9fa3d5eec20
DOI
10.1101/2021.08.03.21261508
Open publication

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Multi-ancestry Multivariate Genome-Wide Analysis Highlights the Role of Common Genetic Variation in Cardiac Structure, Function, and Heart Failure-related TraitsDOI 10.1101/2021.08.03.21261508
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