Article

Leveraging the shared and opposing genetic mechanisms in the heritable cardiomyopathies

2026-01-27

Abstract excerpt

<title>Abstract</title> <p> Dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM) are heart muscle diseases with largely opposing structural and functional phenotypes. Yet, both may lead to the same devastating outcomes of advanced heart failure and life-threatening arrhythmias. Using genome-wide association data from 9,365 DCM cases, 5,900 HCM cases, and over 1.2 million controls, we show that DCM...

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Literature Corpus work: 23c618b2-7910-5d29-97da-259135d5f6df
DOI: 10.21203/rs.3.rs-8346032/v1

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