Article

Common- and rare-variant genetic architecture of heart failure across the allele frequency spectrum

2023-07-18

Abstract excerpt

Heart failure (HF) is a complex trait, influenced by environmental and genetic factors, which affects over 30 million individuals worldwide. Historically, the genetics of HF have been studied in Mendelian forms of disease, where rare genetic variants have been linked to familial cardiomyopathies. More recently, genome-wide association studies (GWAS) have successfully identified common genetic variants associated w...

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Literature Corpus work: 5fe9eb4a-5662-562e-ab34-6858f2451892
DOI: 10.1101/2023.07.16.23292724

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