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Lipopolysaccharide truncation and restoration drives a trade-off in resistance to two phages in <i>Pseudomonas aeruginosa</i>

2026-01-20

Abstract excerpt

Phage therapy is a promising treatment for multidrug resistant bacterial infections, and for patients no longer able to tolerate antibiotic treatments. A major challenge for phage therapy is emergent phage resistance, which target bacteria acquire by structurally modifying or masking phage receptors to prevent adsorption. Functionally diverse phage cocktails that target a broad range of receptors are less prone to...

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Literature Corpus work
8b01d7aa-2bf8-5984-80a5-fd4bb296244c
DOI
10.64898/2026.01.20.700494
Open publication

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Lipopolysaccharide truncation and restoration drives a trade-off in resistance to two phages in <i>Pseudomonas aeruginosa</i>DOI 10.64898/2026.01.20.700494
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