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Article

Screening of the PA14NR Transposon Mutant Library Identifies Genes Involved in Resistance to Bacteriophage Infection in Pseudomomas aeruginosa.

International journal of molecular sciences - 26 Jun 2024

Ho Peiying, Dam Linh Chi, Koh Wei Ren Ryanna, Nai Rui Si, Nah Qian Hui, Rajaie Fizla Faeqa Binte Muhammad, Chan Chia Ching, Aung Thet Tun, Goh Shin Giek, Fang You, Lim Zhining, Koh Ming Guang, Demott Michael, Boucher Yann Felix, Malleret Benoit, Gin Karina Yew-Hoong, Dedon Peter, Moreira Wilfried

Abstract excerpt

Multidrug-resistant P. aeruginosa infections pose a serious public health threat due to the rise in antimicrobial resistance. Phage therapy has emerged as a promising alternative. However, P. aeruginosa has evolved various mechanisms to thwart phage attacks, making it crucial to decipher these resistance mechanisms to develop effective therapeutic strategies. In this study, we conducted a forward-genetic screen...

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Identifiers

PMID: 39000118
DOI: 10.3390/ijms25137009
PMCID: PMC11241198

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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