Article

Intracellular barriers and receptor masking limit success of a <i>Pseudomonas aeruginosa</i> clinical phage family

2026-06-18

Abstract excerpt

Bacteriophage therapy is needed to treat antibiotic resistant infections; however, when a clinical isolate resists a given phage, it is often unclear why. It is therefore currently unknown how to rationally fortify phage therapies to circumvent a priori resistance. Using a family of broad host range therapeutic Pseudomonas aeruginosa phages ( Pbunaviruses) , we show that cell surface receptor masking and intrac...

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Literature Corpus work: 0a9b9e3e-0b87-5f46-9a8e-e11636c1572a
DOI: 10.64898/2026.06.18.732992

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