Article

Predicting the effect of non-coding mutations on single-cell DNA methylation using deep learning

2024-09-07

Abstract excerpt

Predicting the effects of non-coding mutations on DNA methylation is crucial for advancing our understanding of gene expression, epigenetic inheritance, and its role in disease mechanisms. Current methods lack the capability to predict the impact of non-coding mutations on DNA methylation at single-cell resolution and long range, while remain challenges in tracking SNP influences throughout disease progression. He...

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Literature Corpus work: fd5fcbd4-79df-533b-b09b-0b66384ec719
DOI: 10.1101/2024.09.03.611114

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