Article

Mitochondrial Complex II In Intestinal Epithelial Cells Regulates T-cell Mediated Immunopathology

2020-03-12

Abstract excerpt

<h4>Summary</h4> Intestinal epithelial cell (IEC) damage by T cells contributes to alloimmune, autoimmune and iatrogenic diseases such as graft-versus-host disease (GVHD), inflammatory bowel disease (IBD) and immune checkpoint blockade (ICB) mediated colitis, respectively. Despite significant advances in understanding the aberrant biology of T cells in these diseases, little is known about how the fundamental bio...

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Literature Corpus work: 8add8ed5-854e-5506-9a8c-524ff34ffb3c
DOI: 10.1101/2020.03.12.978692

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