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Intestinal epithelial cell metabolism at the interface of microbial dysbiosis and tissue injury

1 Apr 2022

Abstract excerpt

The intestinal epithelium represents the most regenerative tissue in the human body, located in proximity to the dense and functionally diverse microbial milieu of the microbiome. Episodes of tissue injury and incomplete healing of the intestinal epithelium are a prerequisite for immune reactivation and account for recurrent, chronically progressing phenotypes of inflammatory bowel diseases (IBD). Mitochondrial...

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PMID: 35534699
DOI: 10.1038/s41385-022-00514-x

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