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Mitochondrial Function and Microbial Metabolites as Central Regulators of Intestinal Immune Responses and Cancer

29 Jun 2022

Abstract excerpt

Energy and anabolic metabolism are essential for normal cellular homeostasis but also play an important role in regulating immune responses and cancer development as active immune and cancer cells show an altered metabolic profile. Mitochondria take a prominent position in these metabolic reactions. First, most key energetic reactions take place within or in conjunction with mitochondria. Second, mitochondria...

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PMID: 35847099
DOI: 10.3389/fmicb.2022.919424

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