Article

Promoter methylation and gene expression of Pin1 is associated to the risk on Alzheimer’s disease in Southern Chinese

2020-08-25

Abstract excerpt

<h4>Background</h4> Pin1 is a propyl cis-trans isomerase and it has been associated with age-at-onset of Alzheimer’s disease (AD) and other pathological characteristic of AD. DNA methylation is one of the gene regulation and it might affect the gene expression. <h4>Objectives</h4> This study was aimed to examine the correlation between DNA methylation and gene expression of Pin1 and its effect on the risk of AD in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8abad41d-db2a-53c0-9a5f-605d81a6601c
DOI: 10.1101/2020.08.23.20172403

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Promoter methylation and gene expression of Pin1 is associated to the risk on Alzheimer’s disease in Southern ChineseDOI 10.1101/2020.08.23.20172403Read

A PIN1 polymorphism that prevents its suppression by AP4 associates with delayed onset of Alzheimer's disease.Semantic proximity Read

Pin1 Regulatory miRNAs as Novel Candidates for Alzheimer’s Disease TreatmentSemantic proximity Read

Pin1 contribution to Alzheimer's disease: transcriptional and epigenetic mechanisms in patients with late-onset Alzheimer's disease.Semantic proximity Read

PIN1-842G/C and -667T/C polymorphisms are not associated with the susceptibility of Alzheimer's disease: pooled analysis of epidemiologic studies.Semantic proximity Read

Pin1: A New Genetic Link between Alzheimers Disease, Cancer and AgingSemantic proximity Read

DNA sequence variations in the prolyl isomerase Pin1 gene and Alzheimer's disease.Semantic proximity Read

The Pin1 gene polymorphism and the susceptibility of oral squamous cell carcinoma in East China.Semantic proximity Read

Association studies between common variants in prolyl isomerase Pin1 and the risk for late-onset Alzheimer's disease.Semantic proximity Read

Reduced <i>PIN1</i> gene expression in neocortical and limbic brain regions in female Alzheimer’s patients correlates with cognitive and neuropathological phenotypesSemantic proximity Read

PIN1 promoter polymorphisms are associated with Alzheimer's disease.Semantic proximity Read

Pin1 dysregulation helps to explain the inverse association between cancer and Alzheimer's diseaseSemantic proximity Read

PIN-1 promoter polymorphisms in mild cognitive impairment and susceptibility to Alzheimer's disease: a preliminary report.Semantic proximity Read