Article
The Pin1 gene polymorphism and the susceptibility of oral squamous cell carcinoma in East China.
Cancer biomarkers : section A of Disease markers - 1 Jan 2014
Yao Jie, Wang Jian-Ming, Wang Zi-Lu, Wu Yu-Nong
Abstract excerpt
Pin1 is a peptidylprolyl isomerase that specifically recognizes phosphorylated Pro-directed Ser/Thr (pSer/Thr-Pro) peptide sequences. Genetic variants in the Pin1 gene may alter protein function and cancer risk. In this study, we genotyped the two common promoter polymorphisms -842G/C (rs2233678) and -667T/C (rs2233679) in two independent hospital-based case-control studies conducted in Eastern Chinese...
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