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Pin1 Regulatory miRNAs as Novel Candidates for Alzheimer’s Disease Treatment

2018-11-19

Abstract excerpt

Alzheimer’s disease (AD) is the sixth leading cause of death in elderly people whose pathological hallmarks include senile plaques and neurofibrillary tangles (NFTs). The tangles are composed of hyperphosphorylated tau, which is a microtubule-associated protein and its hyperphosphorylation would result in its aggregation and neural cell death. Recently, it has been shown that phosphorylated tau at Thr231 exists in...

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Literature Corpus work
a2a0a1dd-0236-559a-9954-760be724e5e7
DOI
10.1101/472985
Open publication

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Pin1 Regulatory miRNAs as Novel Candidates for Alzheimer’s Disease TreatmentDOI 10.1101/472985
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