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Article

Pin1: A New Genetic Link between Alzheimers Disease, Cancer and Aging

29 Sept 2010

Abstract excerpt

Epidemiologic data suggest that people who develop neurodegenerative diseases of aging have a decreased risk of cancer. This is intriguing, since there is growing evidence that neurodegeneration and carcinogenesis share a number of biological pathways, such as abnormal entry into the cell cycle. The unique enzyme Pin1 plays a key role in the pathogenesis of Alzheimer's disease and many human cancers. Pin1 acts on...

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Identifiers

PMID: 20735350
DOI: 10.2174/1874609811003030158

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Pin1: A New Genetic Link between Alzheimers Disease, Cancer and AgingPMID 20735350Read ↗

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