Article

Metabolomics profiling reveals distinct, sex-specific signatures in the serum and brain metabolomes in the mouse models of Alzheimer’s disease

2023-12-22

Abstract excerpt

<h4>Structured Abstract</h4> <h4>INTRODUCTION</h4> Increasing evidence suggests that metabolic impairments contribute to early Alzheimer’s disease (AD) mechanisms and subsequent dementia. Signals in metabolic pathways conserved across species provides a promising entry point for translation. <h4>METHODS</h4> We investigated differences of serum and brain metabolites between the early-onset 5XFAD and late-onset...

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Literature Corpus work: 8a5ee5ac-f3e1-509c-b332-779ca494cb1d
DOI: 10.1101/2023.12.22.573059

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