Article
Genome-Wide Association Identifies the First Risk Loci for Psychosis in Alzheimer Disease
2020-08-11
Abstract excerpt
Psychotic symptoms, defined as the occurrence of delusions or hallucinations, are frequent in Alzheimer disease (AD with psychosis, AD+P). AD+P affects ∼50% of individuals with AD, identifies a subgroup with poor outcomes, and is associated with a greater degree of cognitive impairment and depressive symptoms, compared to subjects without psychosis (AD-P). Although the estimated heritability of AD+P is 61%, geneti...
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Identifiers and source
- Literature Corpus work
- 8a501f0c-6094-59b8-ad00-632a9973f71a
- DOI
- 10.1101/2020.08.07.20139261