Article
Association between schizophrenia polygenic score and psychotic symptoms in Alzheimer’s disease: meta-analysis of 11 cohort studies
2019-01-26
Abstract excerpt
<h4>Background</h4> Psychosis (delusions and hallucinations) is common in Alzheimer’s disease (AD) and associated with worse clinical outcomes including accelerated cognitive decline and shorter time to nursing home admission. Atypical antipsychotics have limited efficacy which, along with emerging genomic research, suggests some overlapping mechanisms with other disorders characterized by psychosis, like schizop...
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Identifiers and source
- Literature Corpus work
- 95d294cb-6bdd-550f-8f09-2cfe338c5b50
- DOI
- 10.1101/528802