Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease.

doi:10.1038/s41398-019-0592-5

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Article

Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease.

Translational psychiatry - 22 Oct 2019

Creese Byron, Vassos Evangelos, Bergh Sverre, Athanasiu Lavinia, Johar Iskandar, Rongve Arvid, Medbøen Ingrid Tøndel, Vasconcelos Da Silva Miguel, Aakhus Eivind, Andersen Fred, Bettella Francesco, Braekhus Anne, Djurovic Srdjan, Paroni Giulia, Proitsi Petroula, Saltvedt Ingvild, Seripa Davide, Stordal Eystein, Fladby Tormod, Aarsland Dag, Andreassen Ole A, Ballard Clive, Selbaek Geir

Abstract excerpt

Psychosis (delusions or hallucinations) in Alzheimer's disease (AD + P) occurs in up to 50% of individuals and is associated with significantly worse clinical outcomes. Atypical antipsychotics, first developed for schizophrenia, are commonly used in AD + P, suggesting shared mechanisms. Despite this implication, little empirical research has been conducted to examine whether there are mechanistic similarities...

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PMID: 31641104
DOI: 10.1038/s41398-019-0592-5
PMCID: PMC6805870

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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