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Article

Genetic investigation of non-affective psychosis and depression as causal risk factors for dementia.

BMJ mental health - 24 Jun 2026

Escott-Price Valentina, Simmonds Emily, Owen Michael J, O'Donovan Michael

Abstract excerpt

BACKGROUND: Major psychiatric disorders are associated with increased risk of dementia but establishing whether psychiatric disorders causally increase dementia risk is challenging because dementia pathology can precede clinical diagnosis by decades. Prodromal psychiatric symptoms may arise long before cognitive decline, leaving open the possibility of reverse causation. OBJECTIVE: We aimed to determine whether...

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Identifiers

PMID: 42342369
DOI: 10.1136/bmjment-2025-302424
PMCID: PMC13295947

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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