Article

Psychosis in Alzheimer’s Disease is Associated with Excitatory Neuron Vulnerability and Post-Transcriptional Mechanisms Altering Synaptic Protein Levels

2021-09-12

Abstract excerpt

Alzheimer’s disease with psychosis (AD+P) is a phenotypic variant of the disease which is associated with a much more rapid deterioration compared to Alzheimer’s disease without psychosis (AD-P). The neurobiological basis of AD+P is poorly understood. AD is thought to be a disease of the synapse, and our previous studies suggest that those with AD+P have a differentially affected synaptic proteome relative to thos...

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Literature Corpus work: c65584a6-3a3e-52e7-abb4-406c423cce39
DOI: 10.1101/2021.09.07.21262904

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