Article

WNK1 Enhances Migration and Invasion in Breast Cancer Models

2021-03-09

Abstract excerpt

Metastasis is the major cause of mortality in breast cancer patients. Many signaling pathways have been linked to cancer invasiveness, but blockade of few protein components has succeeded in reducing metastasis. Thus, identification of proteins contributing to invasion that are manipulable by small molecules may be valuable in inhibiting spread of the disease. The protein kinase WNK1 (with no lysine (K) 1) has bee...

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Literature Corpus work: 89707768-a725-5234-917f-05d97833ffa6
DOI: 10.1101/2021.03.09.434610

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