Article

Astragaloside IV protest against podocyte injury through upregulating mitophagy via Mfn2/ Pink 1/Parkin axis

2022-06-23

Abstract excerpt

<h4>Background: </h4> Podocyte injury is the most important pathological hallmark of kidney diseases, Autophagy is the critical factors that involve podocyte injury. here we sought to determine whether astragaloside IV (AS-IV) was able to improve renal function and reverse podocyte injury through regulation of autophagy. Methods Using Adriamycin (ADR) mice model and cultured immortalized mouse podocytes, were exp...

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Literature Corpus work: 8944e14a-067c-572c-9c6a-ac28027201d3
DOI: 10.21203/rs.3.rs-1761014/v1

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