Article

DDIT4 mediated autophagy and ferroptosis through VDR-mTOR signaling pathway in the treatment of diabetic kidney disease

2022-11-29

Abstract excerpt

To determine the changes in the expression of DNA damage inducing transcription factor 4 (DDIT4) and the gene related to the activation of vitamin D receptor (VDR) in diabetic kidney disease (DKD) patients and experimental mice, and to explore the molecular mechanism of DDIT4 in the treatment of DKD. The pathological damage of kidney tissue and the molecular expression of VDR-mTOR related pathway in DKD patients a...

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Literature Corpus work: b93c82e3-c1bc-5e2a-99da-a243921b4731
DOI: 10.21203/rs.3.rs-2314736/v1

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