Article
Podocyte injury and repair mechanisms
12 Mar 2015
Abstract excerpt
PURPOSE OF REVIEW: Podocytes are the main gatekeeper of protein filtration in the glomerulus. When podocytes work less efficiently, this translates to the appearance of proteins in the urine, a condition that, if not promptly treated, leads to progression of glomerular damage and renal failure. RECENT FINDINGS: Novel gene mutations have been uncovered in patients with nephrotic syndrome combined with a better...
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