Article
Rutin attenuates oxidative stress via PHB2-mediated mitophagy in MPP + - induced SH-SY5Y cells
2022-07-19
Abstract excerpt
<h4>Background: </h4> and Purpose Oxidative stress plays a crucial role in the occurrence and development of Parkinson's disease (PD). Rutin, a natural botanical ingredient, has been shown to have antioxidant properties. This study aimed to investigate the neuroprotective effect and mechanism of rutin in PD. Methods MPP + (1-methyl-4-phenylpyridinium)-treated SH-SY5Y cells were used as a PD model. SH-SY5Y cells...
Topics
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- Autophagy in Disease and Therapy
- Cholinesterase and Neurodegenerative Diseases
- Endoplasmic Reticulum Stress and Disease
- Ginkgo biloba and Cashew Applications
- Medicinal Plants and Neuroprotection
- Parkinson's Disease Mechanisms and Treatments
- Peptidase Inhibition and Analysis
- Ubiquitin and proteasome pathways
Identifiers and source
- Literature Corpus work
- cdf0ac87-e563-547f-ba8a-dd9bb434e2c2
- DOI
- 10.21203/rs.3.rs-1823351/v1
