Article

Expression quantitative trait locus rs6356 is associated with the susceptibility of heroin addiction by potentially influencing the TH gene expression in the hippocampus and nucleus accumbens

2022-02-21

Abstract excerpt

<title>Abstract</title> <p>Opioid addiction is a complicated and highly heritable brain disease. Dysfunction of dopaminergic signaling is involved in the pathogenesis of addictive disorders. Encoding the synthetase of dopamine, tyrosine hydroxylase (TH) gene has long been an interesting candidate in the genetic association studies for opioid addiction. However, the underlying mechanism of the association of risk...

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Literature Corpus work: 89154741-ec65-5df6-a2f9-ff42844fabcb
DOI: 10.21203/rs.3.rs-1357343/v1

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