Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Elevation of DNA Methylation in the Promoter Regions of the Brain-Derived Neurotrophic Factor Gene is Associated with Heroin Addiction.

Journal of molecular neuroscience : MN - 1 Sept 2021

Xiao Yifan, Zhu Yongsheng, Li Yunxiao

Abstract excerpt

To study the potential role of brain-derived neurotrophic factor (BDNF) methylation in heroin addiction, we first detected the methylation level of seven CpG islands that included 106 CpG sites in the promoter regions of BDNF from 120 people addicted to heroin and 113 controls. Methylation quantitative trait locus (mQTL) analysis was then employed to determine the association between the single-nucleotide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryl Hydrocarbon Receptor Nuclear Translocator
Share to Basic Helix-Loop-Helix Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain-Derived Neurotrophic Factor

Share to CpG Islands

Share to DNA Methylation

Share to Heroin Dependence

Share to Homeodomain Proteins

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 34173192
DOI: 10.1007/s12031-021-01864-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Elevation of DNA Methylation in the Promoter Regions of the Brain-Derived Neurotrophic Factor Gene is Associated with Heroin Addiction.PMID 34173192Read ↗

A significant association between BDNF promoter methylation and the risk of drug addiction.Semantic proximity Read ↗

Expression Quantitative Trait Locus rs6356 Is Associated with Susceptibility to Heroin Addiction by Potentially Influencing TH Gene Expression in the Hippocampus and Nucleus Accumbens.Semantic proximity Read ↗

Expression quantitative trait locus rs6356 is associated with the susceptibility of heroin addiction by potentially influencing the TH gene expression in the hippocampus and nucleus accumbensSemantic proximity Read ↗

Methylation quantitative trait locus rs5326 is associated with susceptibility and effective dosage of methadone maintenance treatment for heroin use disorder.Semantic proximity Read ↗

Methylation and expression quantitative trait locus rs6296 in the HTR1B gene is associated with susceptibility to opioid use disorder.Semantic proximity Read ↗

Polymorphisms of brain-derived neurotrophic factor associated with heroin dependence.Semantic proximity Read ↗

Methylation quantitative locus rs3758653 in the DRD4 gene is associated with duration from first heroin exposure to addiction.Semantic proximity Read ↗

The relationship between polymorphisms of BDNFOS and BDNF genes and heroin addiction in the Han Chinese population.Semantic proximity Read ↗

BDNF DNA methylation changes as a biomarker of psychiatric disorders: literature review and open access database analysis.Semantic proximity Read ↗

Opioid Exposure is Associated with Aberrant DNA Methylation of OPRM1 Promoter Region in a Chinese Han Population.Semantic proximity Read ↗

The BDNF Val66Met polymorphism and plasma brain-derived neurotrophic factor levels in Han Chinese heroin-dependent patients.Semantic proximity Read ↗

BDNF rs6265 polymorphism and drug addiction: a systematic review and meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.