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Article

Multivariate analysis of dopaminergic gene variants as risk factors of heroin dependence.

PloS one - 1 Jan 2013

Vereczkei Andrea, Demetrovics Zsolt, Szekely Anna, Sarkozy Peter, Antal Peter, Szilagyi Agnes, Sasvari-Szekely Maria, Barta Csaba

Abstract excerpt

BACKGROUND: Heroin dependence is a debilitating psychiatric disorder with complex inheritance. Since the dopaminergic system has a key role in rewarding mechanism of the brain, which is directly or indirectly targeted by most drugs of abuse, we focus on the effects and interactions among dopaminergic gene variants. OBJECTIVE: To study the potential association between allelic variants of dopamine D2 receptor...

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Source

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Identifiers

PMID: 23840506
DOI: 10.1371/journal.pone.0066592
PMCID: PMC3696122

Genes

DRD4
COMT
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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