Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Methylation and expression quantitative trait locus rs6296 in the HTR1B gene is associated with susceptibility to opioid use disorder.

Psychopharmacology - 1 Aug 2022

Li Yunxiao, Lu Ye, Xie Qiaoli, Zeng Xiaofeng, Zhang Rui, Dang Wei, Zhu Yongsheng, Zhang Jianbo

Abstract excerpt

Serotonin (5-HT) is implicated in the reward processes underlying substance use disorder. Epigenetic and transcriptional mechanisms contribute to the development of addictive states. To examine the potential mechanisms of 5-HT receptor genes in opioid use disorder, we first determined the associations between several single-nucleotide polymorphism (SNPs) in three representative 5-HT receptor genes (HTR1B, HTR2A,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Methylation
Share to Opioid-Related Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait Loci

Share to Receptor, Serotonin, 5-HT1B

Share to Receptors, Serotonin

Source

Identifiers

PMID: 35438303
DOI: 10.1007/s00213-022-06141-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Methylation and expression quantitative trait locus rs6296 in the HTR1B gene is associated with susceptibility to opioid use disorder.PMID 35438303Read ↗

Methylation quantitative trait locus rs5326 is associated with susceptibility and effective dosage of methadone maintenance treatment for heroin use disorder.Semantic proximity Read ↗

Expression Quantitative Trait Locus rs6356 Is Associated with Susceptibility to Heroin Addiction by Potentially Influencing TH Gene Expression in the Hippocampus and Nucleus Accumbens.Semantic proximity Read ↗

Expression quantitative trait locus rs6356 is associated with the susceptibility of heroin addiction by potentially influencing the TH gene expression in the hippocampus and nucleus accumbensSemantic proximity Read ↗

Associations of the 5-hydroxytryptamine (serotonin) receptor 1B gene (HTR1B) with alcohol, cocaine, and heroin abuse.Semantic proximity Read ↗

Methylation quantitative locus rs3758653 in the DRD4 gene is associated with duration from first heroin exposure to addiction.Semantic proximity Read ↗

Elevation of DNA Methylation in the Promoter Regions of the Brain-Derived Neurotrophic Factor Gene is Associated with Heroin Addiction.Semantic proximity Read ↗

The human serotonin receptor 2B: coding region polymorphisms and association with vulnerability to illegal drug abuse.Semantic proximity Read ↗

SNP-based and haplotype-based genome-wide association on drug dependence in Han Chinese.Semantic proximity Read ↗

Genetics of methamphetamine use disorder: A systematic review and meta-analyses of gene association studies.Semantic proximity Read ↗

Polymorphisms in the 5-hydroxytryptamine receptor 3B gene are associated with heroin dependence in the Chinese Han population.Semantic proximity Read ↗

Association between dopamine D2 receptor gene polymorphisms and the risk of heroin dependence.Semantic proximity Read ↗

Methylation and expression quantitative trait loci rs1799971 in the OPRM1 gene and rs4654327 in the OPRD1 gene are associated with opioid use disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.