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LPAR3 and Col8A1, as matrix stiffness-related biomarkers, promote nasopharyngeal carcinoma metastasis by triggering epithelial-mesenchymal transition and angiogenesis

2023-07-20

Abstract excerpt

<title>Abstract</title> <p>Matrix stiffness affects the progression of nasopharyngeal carcinoma (NPC), but the underlying mechanism is still unknown. It has been demonstrated that the stiffness of collagen fibers deposited in NPC and adjacent tissues differs. Here, we performed RNA-seq analysis of NPC cells cultured on polyacrylamide (PA) hydrogel systems and found that LPAR3 and Col8A1 are potential matrix stiff...

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Literature Corpus work
8914712b-ab8c-5234-8684-d44814deaddf
DOI
10.21203/rs.3.rs-2996230/v1
Open publication

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LPAR3 and Col8A1, as matrix stiffness-related biomarkers, promote nasopharyngeal carcinoma metastasis by triggering epithelial-mesenchymal transition and angiogenesisDOI 10.21203/rs.3.rs-2996230/v1
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