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Age-Driven Lipid Remodeling Activates Lysosome-Mediated Plasma Membrane Repair

2026-01-20

Abstract excerpt

<title>Abstract</title> <p>The abundance and stoichiometry of membrane lipid species vary across a cell’s lifespan and metabolic state. In the retinal pigment epithelium (RPE), age-related alterations in lipid composition contribute to vision loss and diseases such as age-related macular degeneration (AMD), yet the molecular drivers of these changes remain unclear. Here, we show that age-dependent remodeling of t...

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Literature Corpus work
890438f3-6ec1-55bd-973e-9ec534499b60
DOI
10.21203/rs.3.rs-8607320/v1
Open publication

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Age-Driven Lipid Remodeling Activates Lysosome-Mediated Plasma Membrane RepairDOI 10.21203/rs.3.rs-8607320/v1
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