Article

Macrophage signaling and function are regulated by distinct sterol biochemistries

2025-08-11

Abstract excerpt

<h4>ABSTRACT</h4> Membranes require continuous reorganization of lipid components, including sterols, to dynamically alter their rigidity to deform and bend during scission events which occur during fundamental cellular functions such as endocytosis. While diseases of cholesterol biosynthesis result in reduced cellular cholesterol and accumulation of precursor sterols, limited studies have addressed the intracell...

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Identifiers and source

Literature Corpus work: a96f8fef-904a-57e5-8a45-b422e71caaa6
DOI: 10.1101/2025.08.07.669025

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