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Article

ELOVL2: Not just a biomarker of aging

1 Jan 2020

Abstract excerpt

DNA methylation of the ELOVL2 (Elongation Of Very Long Chain Fatty Acids-Like 2) promoter is one of the most robust molecular biomarkers for chronological age, but whether ELOVL2 plays a functional role in aging has not been explored. ELOVL2 encodes a transmembrane protein involved in the synthesis of very long polyunsaturated fatty acids (VLC-PUFAs). These fatty acids play important roles in retinal biology and...

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PMID: 33043173
DOI: 10.1016/j.tma.2020.06.004

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