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Polyunsaturated Fatty Acid - mediated Cellular Rejuvenation for Reversing Age-related Vision Decline

2024-07-02

Abstract excerpt

<h4>ABSTRACT</h4> The retina is uniquely enriched in polyunsaturated fatty acids (PUFAs), which are primarily localized in cell membranes, where they govern membrane biophysical properties such as diffusion, permeability, domain formation, and curvature generation. During aging, alterations in lipid metabolism lead to reduced content of very long-chain PUFAs (VLC-PUFAs) in the retina, and this decline is associat...

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Literature Corpus work
4aee8053-c486-59c6-a55c-eb3235dd0577
DOI
10.1101/2024.07.01.601592
Open publication

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