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Article

A comprehensive review of the family of very-long-chain fatty acid elongases: structure, function, and implications in physiology and pathology

20 Nov 2023

Abstract excerpt

BACKGROUND: The very-long-chain fatty acid elongase (ELOVL) family plays essential roles in lipid metabolism and cellular functions. This comprehensive review explores the structural characteristics, functional properties, and physiological significance of individual ELOVL isoforms, providing insights into lipid biosynthesis, cell membrane dynamics, and signaling pathways. AIM OF REVIEW: This review aims to...

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PMID: 37981715
DOI: 10.1186/s40001-023-01523-7

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