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HOXA7 Promotes Metastasis in KRAS Mutant Colorectal Cancer by Regulating Myeloid-derived Suppressor Cells

2021-11-08

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> KRAS mutation accounts for 30-50% of human colorectal cancer (CRC). Due to paucity of effective treatment options, KRAS mutant CRC is difficult to treat in clinic. Metastasis is still the major reason for the high mortality of KRAS mutant CRC, but the exact mechanism remains unclear. Here, we report a novel role of Homeobox 7 (HOXA7) in promoting KRAS mutant CRC...

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Literature Corpus work
88f5d706-dfe8-584e-837f-61d9c371c822
DOI
10.21203/rs.3.rs-1042676/v1
Open publication

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HOXA7 Promotes Metastasis in KRAS Mutant Colorectal Cancer by Regulating Myeloid-derived Suppressor CellsDOI 10.21203/rs.3.rs-1042676/v1
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