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Article

Alteration of FBXW7 is Associated with Worse Survival in Patients Undergoing Resection of Colorectal Liver Metastases.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract - 1 Jan 2021

Kawaguchi Yoshikuni, Newhook Timothy E, Tran Cao Hop S, Tzeng Ching-Wei D, Chun Yun Shin, Aloia Thomas A, Dasari Arvind, Kopetz Scott, Vauthey Jean-Nicolas

Abstract excerpt

BACKGROUND: For patients undergoing resection of colorectal liver metastases (CLMs), the prognostic role of somatic gene alterations is increasingly recognized. F-box/WD repeat-containing protein 7 (FBXW7) is a tumor suppressor gene found in approximately 10% of patients with colorectal cancer. The aim of this study is to assess the association of FBXW7 with overall survival after CLM resection. METHODS: Patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33205306
DOI: 10.1007/s11605-020-04866-2
PMCID: PMC10095595

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